ID   CHLA-150
AC   CVCL_A059
DR   cancercelllines; CVCL_A059
DR   Cosmic; 930057
DR   Cosmic; 1019936
DR   Cosmic; 1161985
DR   Wikidata; Q54812167
RX   PubMed=11212268;
RX   PubMed=16822308;
RX   PubMed=18724359;
CC   Sequence variation: Mutation; HGNC; HGNC:427; ALK; Simple; p.Arg1275Gln (c.3824G>A); ClinVar=VCV000018083; Zygosity=Unspecified (PubMed=18724359).
ST   Source(s): COG
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 8,13
ST   D16S539: 9
ST   D18S51: 13,14
ST   D19S433: 15
ST   D21S11: 30.2,31
ST   D2S1338: 23,25
ST   D3S1358: 14,17
ST   D5S818: 11
ST   D7S820: 8,11
ST   D8S1179: 13,16
ST   FGA: 20,23
ST   TH01: 8,9.3
ST   TPOX: 8,11
ST   vWA: 15,16
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Children
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=11212268;
RA   Thompson P.M., Maris J.M., Hogarty M.D., Seeger R.C., Reynolds C.P.,
RA   Brodeur G.M., White P.S.;
RT   "Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36
RT   or at other tumor suppressor loci in neuroblastoma.";
RL   Cancer Res. 61:679-686(2001).
//
RX   PubMed=16822308; DOI=10.1186/1471-2407-6-177; PMCID=PMC1533846;
RA   Dam V., Morgan B.T., Mazanek P., Hogarty M.D.;
RT   "Mutations in PIK3CA are infrequent in neuroblastoma.";
RL   BMC Cancer 6:177.1-177.10(2006).
//
RX   PubMed=18724359; DOI=10.1038/nature07261; PMCID=PMC2672043;
RA   Mosse Y.P., Laudenslager M., Longo L., Cole K.A., Wood A.,
RA   Attiyeh E.F., Laquaglia M.J., Sennett R., Lynch J.E., Perri P.,
RA   Laureys G., Speleman F., Kim C., Hou C.-P., Hakonarson H., Torkamani A.,
RA   Schork N.J., Brodeur G.M., Tonini G.P., Rappaport E., Devoto M.,
RA   Maris J.M.;
RT   "Identification of ALK as a major familial neuroblastoma
RT   predisposition gene.";
RL   Nature 455:930-935(2008).
//