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Cellosaurus HSG-AZA3 (CVCL_A048)

[Text version]
Cell line name HSG-AZA3
Synonyms AZA3; AZA-3
Accession CVCL_A048
Resource Identification Initiative To cite this cell line use: HSG-AZA3 (RRID:CVCL_A048)
Comments Problematic cell line: Contaminated. Parent cell line (HSG) has been shown to be a HeLa derivative (PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00315.
Population: African American.
Selected for resistance to: ChEBI; CHEBI_2038; 5-azacytidine (5-azaC).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Proteome analysis by 2D-DE/MS.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2517 (HSG)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): JCRB=CHB0002

Markers:
AmelogeninX
CSF1PO9
D5S81811
D7S8208,12
D13S31712,13.3
D16S5399,10
TH017
TPOX8,12
vWA16,18,19

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=2440567
Sato M., Azuma M., Hayashi Y., Yoshida H., Yanagawa T., Yura Y.
5-azacytidine induction of stable myoepithelial and acinar cells from a human salivary intercalated duct cell clone.
Cancer Res. 47:4453-4459(1987)

DOI=10.1007/0-306-46872-7_9
Sato M.
Salivary gland tumors.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.161-178; Kluwer Academic Publishers; New York; USA (1999)

PubMed=16391823; DOI=10.3892/ijmm.17.2.253
Kasamatsu A., Uzawa K., Nakashima D., Kouzu Y., Endo Y., Koike H., Yokoe H., Harada K., Sato M., Tanzawa H.
A proteomics approach to characterizing human submandibular gland cell lines by fluorescent two-dimensional differential in-gel electrophoresis.
Int. J. Mol. Med. 17:253-260(2006)

PubMed=17390010; DOI=10.3892/ijo.30.5.1089
Kawamata H., Omotehara F., Nakashiro K.-i., Uchida D., Shinagawa Y., Tachibana M., Imai Y., Fujimori T.
Oncogenic mutation of the p53 gene derived from head and neck cancer prevents cells from undergoing apoptosis after DNA damage.
Int. J. Oncol. 30:1089-1097(2007)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) JCRB; CHB0002 - Discontinued
Biological sample resources BioSample; SAMN03151714
Encyclopedic resources Wikidata; Q54896447
Polymorphism and mutation databases IARC_TP53; 25035
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number22