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Cellosaurus HSG-AZA3 (CVCL_A048)

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Cell line name HSG-AZA3
Synonyms AZA3; AZA-3
Accession CVCL_A048
Resource Identification Initiative To cite this cell line use: HSG-AZA3 (RRID:CVCL_A048)
Comments Problematic cell line: Contaminated. Parent cell line (HSG) has been shown to be a HeLa derivative (PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00315.
Population: African American.
Selected for resistance to: ChEBI; CHEBI_2038; 5-azacytidine (5-azaC).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Proteomics; 2DE-MS.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2517 (HSG)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): JCRB=CHB0002

Markers:
AmelogeninX
CSF1PO9
D5S81811
D7S8208,12
D13S31712,13.3
D16S5399,10
TH017
TPOX8,12
vWA16,18,19

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=2440567
Mitsunobu Sato, Masayuki Azuma, Yoshio Hayashi, Hideo Yoshida, Tetsuo Yanagawa, Yoshiaki Yura;
5-azacytidine induction of stable myoepithelial and acinar cells from a human salivary intercalated duct cell clone.
Cancer Res. 47:4453-4459(1987)

DOI=10.1007/0-306-46872-7_9
Mitsunobu Sato;
Salivary gland tumors.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.161-178; Kluwer Academic Publishers; New York; USA (1999)

PubMed=16391823; DOI=10.3892/ijmm.17.2.253
Atsushi Kasamatsu, Katsuhiro Uzawa, Dai Nakashima, Yukinao Kouzu, Yosuke Endo, Hirofumi Koike, Hidetaka Yokoe, Koji Harada, Mitsunobu Sato, Hideki Tanzawa;
A proteomics approach to characterizing human submandibular gland cell lines by fluorescent two-dimensional differential in-gel electrophoresis.
Int. J. Mol. Med. 17:253-260(2006)

PubMed=17390010; DOI=10.3892/ijo.30.5.1089
Hitoshi Kawamata, Fumie Omotehara, Koh-ichi Nakashiro, Daisuke Uchida, Yasuhiro Shinagawa, Masatsugu Tachibana, Yutaka Imai, Takahiro Fujimori;
Oncogenic mutation of the p53 gene derived from head and neck cancer prevents cells from undergoing apoptosis after DNA damage.
Int. J. Oncol. 30:1089-1097(2007)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) JCRB; CHB0002 - Discontinued
Biological sample resources BioSample; SAMN03151714
Encyclopedic resources Wikidata; Q54896447
Polymorphism and mutation databases IARC_TP53; 25035
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number23