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Cellosaurus BCC-1/KMC (CVCL_A033)

[Text version]
Cell line name BCC-1/KMC
Synonyms BCC1/KMC
Accession CVCL_A033
Resource Identification Initiative To cite this cell line use: BCC-1/KMC (RRID:CVCL_A033)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from a 65 year old female patient with a skin basal cell carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00112.
Population: African American.
Doubling time: 38.86 hours (PubMed=8007045).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

Chiang L.-C., Chiang W., Yu H.-S., Sheu H.-M., Chen H.-Y.
Establishment and characterization of a continuous human basal cell carcinoma cell line from facial skin (I) cytological behavior of early passages.
Gaoxiong Yi Xue Ke Xue Za Zhi 10:170-176(1994)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=17587681; DOI=10.1271/bbb.70008
Cherng J.-M., Shieh D.-E., Chiang W., Chang M.-Y., Chiang L.-C.
Chemopreventive effects of minor dietary constituents in common foods on human cancer cells.
Biosci. Biotechnol. Biochem. 71:1500-1504(2007)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151666
Encyclopedic resources Wikidata; Q54795337
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number20