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Cellosaurus PC14PE6/AS2 (CVCL_9W72)

[Text version]
Cell line name PC14PE6/AS2
Accession CVCL_9W72
Resource Identification Initiative To cite this cell line use: PC14PE6/AS2 (RRID:CVCL_9W72)
Comments Problematic cell line: Contaminated. Grand-parent cell line (PC-14) has been shown to be a PC-9 derivative.
Population: Japanese.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9W70 (PC14PE6)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line

PubMed=16518408; DOI=10.1038/sj.onc.1209464
Yeh H.-H., Lai W.-W., Chen H.H.W., Liu H.-S., Su W.-C.
Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion.
Oncogene 25:4300-4309(2006)

Cell line databases/resources cancercelllines; CVCL_9W72
Encyclopedic resources Wikidata; Q54938561
Entry history
Entry creation23-Feb-2016
Last entry update05-Oct-2023
Version number14