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Cellosaurus T2.DR3 (CVCL_9W17)

[Text version]
Cell line name T2.DR3
Synonyms T2/DR3; T2DR3
Accession CVCL_9W17
Resource Identification Initiative To cite this cell line use: T2.DR3 (RRID:CVCL_9W17)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4948; HLA-DRB1 (Note=Allele DRB1*03:01).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2211 (T2)
Children:
CVCL_9W18 (T2.DR3/DM)
Category Hybrid cell line
Publications

PubMed=1373173; DOI=10.4049/jimmunol.148.8.2586
Riberdy J.M., Cresswell P.
The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation.
J. Immunol. 148:2586-2590(1992)

PubMed=7600288; DOI=10.1016/1074-7613(94)90049-3
Denzin L.K., Robbins N.F., Carboy-Newcomb C., Cresswell P.
Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells.
Immunity 1:595-606(1994)

PubMed=8195723; DOI=10.1084/jem.179.6.2017; PMCID=PMC2191518
Kovats S., Drover S., Marshall W.H., Freed D., Whiteley P.E., Nepom G.T., Blum J.S.
Coordinate defects in human histocompatibility leukocyte antigen class II expression and antigen presentation in bare lymphocyte syndrome.
J. Exp. Med. 179:2017-2022(1994)

Cross-references
Encyclopedic resources Wikidata; Q54971434
Entry history
Entry creation23-Feb-2016
Last entry update19-Dec-2024
Version number5