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Cellosaurus MCF-hGH (CVCL_9V74)

[Text version]
Cell line name MCF-hGH
Synonyms MCF-HGH
Accession CVCL_9V74
Resource Identification Initiative To cite this cell line use: MCF-hGH (RRID:CVCL_9V74)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:4261; GH1.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=10388519; DOI=10.1006/excr.1999.4492
Kaulsay K.K., Mertani H.C., Tornell J., Morel G., Lee K.-O., Lobie P.E.
Autocrine stimulation of human mammary carcinoma cell proliferation by human growth hormone.
Exp. Cell Res. 250:35-50(1999)

Cross-references
Cell line collections (Providers) NCBI_Iran; C628
Cell line databases/resources cancercelllines; CVCL_9V74
Encyclopedic resources Wikidata; Q54904411
Entry history
Entry creation23-Feb-2016
Last entry update19-Dec-2024
Version number15