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Cellosaurus KDI/20 (CVCL_9V30)

[Text version]
Cell line name KDI/20
Accession CVCL_9V30
Resource Identification Initiative To cite this cell line use: KDI/20 (RRID:CVCL_9V30)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=17852455; DOI=10.1080/10245330701283991
Nadali F., Pourfathollah A.A., Alimoghaddam K., Nikougoftar M., Rostami S., Dizaji A., Azizi E., Zomorodipour A., Ghavamzadeh A.
Multidrug resistance inhibition by antisense oligonucleotide against MDR1/mRNA in P-glycoprotein expressing leukemic cells.
Hematology 12:393-401(2007)

Cross-references
Cell line collections (Providers) NCBI_Iran; C637
Encyclopedic resources Wikidata; Q54899708
Entry history
Entry creation23-Feb-2016
Last entry update02-May-2024
Version number15