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Cellosaurus TELCeB6 (CVCL_9U66)

[Text version]
Cell line name TELCeB6
Accession CVCL_9U66
Resource Identification Initiative To cite this cell line use: TELCeB6 (RRID:CVCL_9U66)
Comments Group: Retrovirus packaging cell line.
Problematic cell line: Contaminated. Grand-parent cell line (TE 671) has been shown to be a RD derivative.
Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03355; Moloney murine leukemia virus (MoMLV) gag-pol.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9U65 (TELac2)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=7494248; DOI=10.1128/JVI.69.12.7430-7436.1995; PMCID=PMC189680
Cosset F.-L., Takeuchi Y., Battini J.-L., Weiss R.A., Collins M.K.L.
High-titer packaging cells producing recombinant retroviruses resistant to human serum.
J. Virol. 69:7430-7436(1995)

PubMed=10022544; DOI=10.1089/10430349950018986
Duisit G., Salvetti A., Moullier P., Cosset F.-L.
Functional characterization of adenoviral/retroviral chimeric vectors and their use for efficient screening of retroviral producer cell lines.
Hum. Gene Ther. 10:189-200(1999)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9U66
Encyclopedic resources Wikidata; Q54972051
Entry history
Entry creation23-Feb-2016
Last entry update19-Dec-2024
Version number15