ID   OV-4453
AC   CVCL_9T20
SY   OV4453
DR   cancercelllines; CVCL_9T20
DR   Wikidata; Q54936830
RX   PubMed=26622941;
CC   Doubling time: 2.44 +- 0.03 days (PubMed=26622941).
CC   Sequence variation: Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Glu1953Ter (c.5857G>T); ClinVar=VCV000051952; Zygosity=Unspecified (PubMed=26622941).
CC   Sequence variation: Mutation; HGNC; HGNC:19291; CSMD3; Simple; p.Ser646Thr (c.1937G>C); Zygosity=Unspecified (PubMed=26622941).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; c.2490-5_2490-1del5; Zygosity=Unspecified (PubMed=26622941).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Unspecified; Note=Splice acceptor mutation (PubMed=26622941).
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Miscellaneous: STR profile from personal communication of Mes-Masson, Anne-Marie.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 12
ST   D16S539: 12
ST   D21S11: 30,31
ST   D5S818: 9
ST   D7S820: 8,11
ST   TH01: 7
ST   TPOX: 8
ST   vWA: 14,18
DI   NCIt; C36101; BRCA2-associated hereditary breast and ovarian cancer syndrome
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
DI   ORDO; Orphanet_145; Hereditary breast and ovarian cancer syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   70Y
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 19-12-24; Version: 16
//
RX   PubMed=26622941; DOI=10.18632/genesandcancer.76; PMCID=PMC4633166;
RA   Fleury H., Communal L., Carmona E., Portelance L., Arcand S.L.,
RA   Rahimi K., Tonin P.N., Provencher D.M., Mes-Masson A.-M.;
RT   "Novel high-grade serous epithelial ovarian cancer cell lines that
RT   reflect the molecular diversity of both the sporadic and hereditary
RT   disease.";
RL   Genes Cancer 6:378-398(2015).
//