ID   MSU-1.0
AC   CVCL_9S99
SY   MSU 1.0; MSU1.0
DR   TOKU-E; 4098
DR   Wikidata; Q54906901
RX   DOI=10.1007/978-1-4612-0411-4_35;
RX   PubMed=1915659;
RX   PubMed=11888918;
RX   PubMed=18048363;
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P01110; Avian myelocytomatosis virus MC29 v-Myc.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: v-Myc.
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Fibroblast of foreskin; CL=CL_1001608.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_XG18 ! LG1
SX   Male
AG   <1M
CA   Transformed cell line
DT   Created: 23-02-16; Last updated: 19-12-24; Version: 11
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RX   DOI=10.1007/978-1-4612-0411-4_35;
RA   McCormick J.J., Maher V.M.;
RT   "Malignant transformation of human fibroblasts in vitro.";
RL   (In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim J.S., Dritschilo A. (eds.); pp.347-357; Humana Press; New York; USA (1990).
//
RX   PubMed=1915659; DOI=10.1016/0014-4827(91)90489-H;
RA   Morgan T.L., Yang D.-J., Fry D.G., Hurlin P.J., Kohler S.K.,
RA   Maher V.M., McCormick J.J.;
RT   "Characteristics of an infinite life span diploid human fibroblast
RT   cell strain and a near-diploid strain arising from a clone of cells
RT   expressing a transfected v-myc oncogene.";
RL   Exp. Cell Res. 197:125-136(1991).
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RX   PubMed=11888918;
RA   Havre P.A., O'Reilly S., McCormick J.J., Brash D.E.;
RT   "Transformed and tumor-derived human cells exhibit preferential
RT   sensitivity to the thiol antioxidants, N-acetyl cysteine and
RT   penicillamine.";
RL   Cancer Res. 62:1443-1449(2002).
//
RX   PubMed=18048363; DOI=10.1074/jbc.M709046200;
RA   Lito P., Mets B.D., Kleff S., O'Reilly S., Maher V.M., McCormick J.J.;
RT   "Evidence that sprouty 2 is necessary for sarcoma formation by H-Ras
RT   oncogene-transformed human fibroblasts.";
RL   J. Biol. Chem. 283:2002-2009(2008).
//