Cell line name |
IK-90 |
Accession |
CVCL_9996 |
Resource Identification Initiative |
To cite this cell line use: IK-90 (RRID:CVCL_9996) |
Comments |
Population: Japanese. Derived from site: In situ; Endometrium; UBERON=UBERON_0001295. |
Sequence variations |
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex10del; Zygosity=Heterozygous (PubMed=8105795).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (PubMed=8105795).
|
Disease |
Type I endometrial adenocarcinoma (NCIt: C40145) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_2529 (Ishikawa) |
Sex of cell |
Female |
Age at sampling |
39Y |
Category |
Cancer cell line |
Publications | PubMed=3815380 Terakawa N., Hayashida M., Shimizu I., Ikegami H., Wakimoto H., Aono T., Tanizawa O., Matsumoto K., Nishida M. Growth inhibition by progestins in a human endometrial cancer cell line with estrogen-independent progesterone receptors. Cancer Res. 47:1918-1923(1987) PubMed=8105795; DOI=10.1002/mc.2940080303 Enomoto T., Fujita M., Inoue M., Nakazawa-Miyamoto A., Tanizawa O., Nomura T. Alterations of the Rb gene and its association with Ki-ras activation and p53 inactivation in endometrial adenocarcinoma. Mol. Carcinog. 8:132-137(1993) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_9996
|
Encyclopedic resources |
Wikidata; Q54897451
|
Polymorphism and mutation databases |
Cosmic; 735334
IARC_TP53; 2379
|
Entry history |
Entry creation | 06-Jun-2012 |
Last entry update | 19-Dec-2024 |
Version number | 13 |
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