ID   ch-2879
AC   CVCL_9921
SY   CH-2879; CH2879
DR   Cosmic; 1602477
DR   Cosmic; 1992324
DR   IARC_TP53; 27034
DR   Wikidata; Q54811597
RX   PubMed=12808123;
RX   PubMed=19787792;
RX   PubMed=22057234;
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=19787792).
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; None_reported; -; Zygosity=- (PubMed=22057234).
CC   Sequence variation: Mutation; HGNC; HGNC:5383; IDH2; None_reported; -; Zygosity=- (PubMed=22057234).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=19787792).
CC   Derived from site: In situ; Bone, rib; UBERON=UBERON_0002228.
ST   Source(s): PubMed=19787792
ST   Amelogenin: X
ST   D16S539: 8,9
ST   D18S51: 12
ST   D19S433: 14
ST   D21S11: 30,32.2
ST   D2S1338: 17
ST   D3S1358: 16
ST   D5S818: 12
ST   D8S1179: 12
ST   FGA: 22
ST   SE33: 32.2
ST   TH01: 8
ST   TPOX: 10,11
ST   vWA: 16
DI   NCIt; C7155; Primary central chondrosarcoma
DI   ORDO; Orphanet_55880; Chondrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   35Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 21
//
RX   PubMed=12808123; DOI=10.1097/01.LAB.0000073131.34648.EA;
RA   Gil-Benso R., Lopez-Gines C., Lopez-Guerrero J.A., Carda C.,
RA   Callaghan R.C., Navarro S., Ferrer J., Pellin A., Llombart-Bosch A.;
RT   "Establishment and characterization of a continuous human
RT   chondrosarcoma cell line, ch-2879: comparative histologic and genetic
RT   studies with its tumor of origin.";
RL   Lab. Invest. 83:877-887(2003).
//
RX   PubMed=19787792; DOI=10.1002/gcc.20717;
RA   Ottaviano L., Schaefer K.-L., Gajewski M., Huckenbeck W., Baldus S.E.,
RA   Rogel U., Mackintosh C., de Alava E., Myklebost O., Kresse S.H.,
RA   Meza-Zepeda L.A., Serra M., Cleton-Jansen A.-M., Hogendoorn P.C.W.,
RA   Buerger H., Aigner T., Gabbert H.E., Poremba C.;
RT   "Molecular characterization of commonly used cell lines for bone tumor
RT   research: a trans-European EuroBoNet effort.";
RL   Genes Chromosomes Cancer 49:40-51(2010).
//
RX   PubMed=22057234; DOI=10.1038/ng.1004; PMCID=PMC3427908;
RA   Marfatia T., van Eijk R., d'Adamo P., van Ruler M.A.J.H.,
RA   Kuijjer M.L., Oosting J., Cleton-Jansen A.-M., van Oosterwijk J.G.,
RA   Verbeke S.L.J., Meijer D., van Wezel T., Nord K.H., Sangiorgi L.,
RA   Toker B., Liegl-Atzwanger B., San-Julian M., Sciot R., Limaye N.,
RA   Kindblom L.-G., Daugaard S., Godfraind C., Boon L.M., Vikkula M.,
RA   Kurek K.C., Szuhai K., French P.J., Bovee J.V.M.G.;
RT   "Somatic mosaic IDH1 and IDH2 mutations are associated with
RT   enchondroma and spindle cell hemangioma in Ollier disease and Maffucci
RT   syndrome.";
RL   Nat. Genet. 43:1256-1261(2011).
//