ID   GLAG-66
AC   CVCL_9918
DR   BTO; BTO:0006406
DR   cancercelllines; CVCL_9918
DR   Wikidata; Q54835892
RX   PubMed=8330267;
RX   PubMed=19087340;
CC   Population: Caucasian; Italian.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from child cell line K1).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu542Lys (c.1624G>A); ClinVar=VCV000031944; Zygosity=Heterozygous (from child cell line K1).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (from child cell line K1).
CC   Derived from site: Metastatic; Thyroid gland; UBERON=UBERON_0002046.
DI   NCIt; C4035; Thyroid gland papillary carcinoma
DI   ORDO; Orphanet_146; Differentiated thyroid carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 19
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RX   PubMed=8330267; DOI=10.1016/0165-4608(93)90163-G;
RA   Antonini P., Linares G., Gaillard N., Venuat A.-M., Schlumberger M.,
RA   Travagli J.-P., Caillou B., Berger R., Parmentier C.;
RT   "Cytogenetic characterization of a new human papillary thyroid
RT   carcinoma permanent cell line (GLAG-66).";
RL   Cancer Genet. Cytogenet. 67:117-122(1993).
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RX   PubMed=19087340; DOI=10.1186/1471-2407-8-371;
RA   Ribeiro F.R., Meireles A.M., Rocha A.S., Teixeira M.R.;
RT   "Conventional and molecular cytogenetics of human non-medullary
RT   thyroid carcinoma: characterization of eight cell line models and
RT   review of the literature on clinical samples.";
RL   BMC Cancer 8:371.1-371.11(2008).
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