ID   UKF-NB-2rDOX100
AC   CVCL_9909
SY   UKF-NB-2 DOXO
DR   Wikidata; Q54990294
RX   PubMed=12532417;
RX   PubMed=16151587;
RX   PubMed=17505515;
WW   https://www.wass-michaelislab.org/rccl.php
CC   Part of: Resistant Cancer Cell Line (RCCL) collection.
CC   Doubling time: 21 hours (PubMed=12532417).
CC   Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9902 ! UKF-NB-2
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 14
//
RX   PubMed=12532417; DOI=10.1002/ijc.10917;
RA   Kotchetkov R., Cinatl J., Blaheta R.A., Vogel J.-U., Karaskova J.,
RA   Squire J.A., Hernaiz Driever P., Klingebiel T., Cinatl J. Jr.;
RT   "Development of resistance to vincristine and doxorubicin in
RT   neuroblastoma alters malignant properties and induces additional
RT   karyotype changes: a preclinical model.";
RL   Int. J. Cancer 104:36-43(2003).
//
RX   PubMed=16151587;
RA   Bedrnicek J., Vicha A., Jarosova M., Holzerova M., Cinatl J. Jr.,
RA   Michaelis M., Cinatl J., Eckschlager T.;
RT   "Characterization of drug-resistant neuroblastoma cell lines by
RT   comparative genomic hybridization.";
RL   Neoplasma 52:415-419(2005).
//
RX   PubMed=17505515; DOI=10.1038/sj.bjc.6603777;
RA   Blaheta R.A., Michaelis M., Natsheh I., Hasenberg C., Weich E.,
RA   Relja B., Jonas D., Doerr H.-W., Cinatl J. Jr.;
RT   "Valproic acid inhibits adhesion of vincristine- and cisplatin-resistant
RT   neuroblastoma tumour cells to endothelium.";
RL   Br. J. Cancer 96:1699-1706(2007).
//