Cellosaurus cell line BJAB-K3 (CVCL

Cellosaurus BJAB-K3 (CVCL_9876)

Cross-references
Cell line name	BJAB-K3
Synonyms	BJAB/K3; BJABK3
Accession	CVCL_9876
Resource Identification Initiative	To cite this cell line use: BJAB-K3 (RRID:CVCL_9876)
Comments	Population: African; Kenyan. Virology: EBV-negative. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P12978; Epstein-Barr virus (strain B95-8) EBNA2. Derived from site: In situ; Groin; UBERON=UBERON_0008337. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Mutation; HGNC; 11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease	Burkitt lymphoma (NCIt: C2912) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_5711 (BJAB)
Sex of cell	Female
Age at sampling	5Y
Category	Cancer cell line
Publications	PubMed=8627226; DOI=10.1099/0022-1317-77-2-227 Kempkes B., Zimber-Strobl U., Eissner G., Pawlita M., Falk M.H., Hammerschmidt W., Bornkamm G.-W. Epstein-Barr virus nuclear antigen 2 (EBNA2)-oestrogen receptor fusion proteins complement the EBNA2-deficient Epstein-Barr virus strain P3HR1 in transformation of primary B cells but suppress growth of human B cell lymphoma lines. J. Gen. Virol. 77:227-237(1996) PubMed=17166914; DOI=10.1128/JVI.01961-06; PMCID=PMC1865953 Li Q.-L., Means R.E., Lang S., Jung J.U. Downregulation of gamma interferon receptor 1 by Kaposi's sarcoma-associated herpesvirus K3 and K5. J. Virol. 81:2117-2127(2007)
Cell line databases/resources	cancercelllines; CVCL_9876
Encyclopedic resources	Wikidata; Q54796993
Experimental variables resources	EFO; EFO_0001090
Entry history
Entry creation	06-Jun-2012
Last entry update	10-Sep-2024
Version number	18