AC   CVCL_9569
DR   BioSample; SAMN03151616
DR   HIVReagentProgram; ARP-9402
DR   Wikidata; Q54954867
RX   DOI=10.1007/0-306-46861-1_10;
RX   PubMed=7520247;
RX   PubMed=22987579;
CC   Problematic cell line: Contaminated. Shown to be a Caki-1 derivative (PubMed=22987579). Originally thought to originate from a 28 year old male patient with HIV-1 negative Kaposi sarcoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00477.
CC   Population: Caucasian.
CC   Doubling time: 24-36 hours (PubMed=7520247).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Leu98Pro (c.293T>C); ClinVar=VCV001502192; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
ST   Source(s): PubMed=22987579
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 11,12
ST   D16S539: 12
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   TH01: 6,8
ST   TPOX: 8,11
ST   vWA: 15,17
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0234 ! Caki-1
SX   Male
AG   49Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 23
RX   DOI=10.1007/0-306-46861-1_10;
RA   Boshoff C.;
RT   "Kaposi's sarcoma.";
RL   (In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.157-166; Kluwer Academic Publishers; New York (1999).
RX   PubMed=7520247; DOI=10.1097/00002030-199405000-00002;
RA   Herndier B.G., Werner A., Arnstein P., Abbey N.W., Demartis F.,
RA   Cohen R.L., Shuman M.A., Levy J.A.;
RT   "Characterization of a human Kaposi's sarcoma cell line that induces
RT   angiogenic tumors in animals.";
RL   AIDS 8:575-581(1994).
RX   PubMed=22987579; DOI=10.1002/ijc.27849;
RA   Sturzl M., Gaus D., Dirks W.G., Ganem D.E., Jochmann R.;
RT   "Kaposi's sarcoma-derived cell line SLK is not of endothelial origin,
RT   but is a contaminant from a known renal carcinoma cell line.";
RL   Int. J. Cancer 132:1954-1958(2013).