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Cellosaurus SN12C-PM6 (CVCL_9549)

[Text version]
Cell line name SN12C-PM6
Synonyms SN12CPM6; SN12-PM6; SN12PM6; PM6; LM1
Accession CVCL_9549
Resource Identification Initiative To cite this cell line use: SN12C-PM6 (RRID:CVCL_9549)
Comments Population: Caucasian.
Omics: CNV analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu336Ter (c.1006G>T); Zygosity=Homozygous (from parent cell line).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1705 (SN12C)
Children:
CVCL_DG80 (SN12C-PM6-2)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=2706827; DOI=10.1007/BF01753659
Naito S., Walker S.M., Fidler I.J.
In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice.
Clin. Exp. Metastasis 7:381-389(1989)

PubMed=8053494; PMCID=PMC1887407
Singh R.K., Bucana C.D., Gutman M., Fan D., Wilson M.R., Fidler I.J.
Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells.
Am. J. Pathol. 145:365-374(1994)

PubMed=10987313
Yano S., Shinohara H., Herbst R.S., Kuniyasu H., Bucana C.D., Ellis L.M., Davis D.W., McConkey D.J., Fidler I.J.
Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.
Cancer Res. 60:4959-4967(2000)

PubMed=20952505; DOI=10.1158/0008-5472.CAN-10-2279; PMCID=PMC3281492
Lopez-Lago M.A., Thodima V.J., Guttapalli A., Chan T., Heguy A., Molina A.M., Reuter V.E., Motzer R.J., Chaganti R.S.K.
Genomic deregulation during metastasis of renal cell carcinoma implements a myofibroblast-like program of gene expression.
Cancer Res. 70:9682-9692(2010)

Cross-references
Cell line collections (Providers) KCLB; 80026
Cell line databases/resources cancercelllines; CVCL_9549
Encyclopedic resources Wikidata; Q54955020
Gene expression databases GEO; GSM374474
GEO; GSM579206
GEO; GSM579401
Polymorphism and mutation databases Progenetix; CVCL_9549
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18