Cell line name |
LAMA-88 |
Synonyms |
Lama-88; LAMA88 |
Accession |
CVCL_9540 |
Resource Identification Initiative |
To cite this cell line use: LAMA-88 (RRID:CVCL_9540) |
Comments |
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. |
Sequence variations |
- Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (PubMed=10071072; PubMed=10576511).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys319Ter (c.955A>T); Zygosity=Homozygous (from parent cell line).
|
Disease |
Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174) Chronic myeloid leukemia (ORDO: Orphanet_521) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0388 (LAMA-84) |
Sex of cell |
Female |
Age at sampling |
29Y |
Category |
Cancer cell line |
Publications | PubMed=7996872; DOI=10.1016/0145-2126(94)90102-3 Champelovier P., Valiron O., Jacrot M., Leroux D., Seigneurin D. Selection and characterization of an erythroeosinophilic subclone (LAMA-87) and an eosinophilic subclone (LAMA-88) from the multipotential cell line LAMA-84. Leuk. Res. 18:903-918(1994) PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4 Drexler H.G., MacLeod R.A.F., Uphoff C.C. Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia. Leuk. Res. 23:207-215(1999) PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9 Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G. ABL-BCR expression in BCR-ABL-positive human leukemia cell lines. Leuk. Res. 23:1055-1060(1999) DOI=10.1016/B978-0-12-221970-2.50457-5 Drexler H.G. The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001) |
Cross-references |
Encyclopedic resources |
Wikidata; Q54901916
|
Entry history |
Entry creation | 06-Jun-2012 |
Last entry update | 19-Dec-2024 |
Version number | 16 |
---|