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Cellosaurus SMS-LHN (CVCL_9539)

[Text version]
Cell line name SMS-LHN
Accession CVCL_9539
Resource Identification Initiative To cite this cell line use: SMS-LHN (RRID:CVCL_9539)
Comments Characteristics: Neuroblastic type (N-type) (PubMed=15720811).
Doubling time: 216 hours (COG).
Omics: Array-based CGH.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817,19
D3S135816,18
D5S81810,11
D7S8208,11
D8S117913,14
D13S3179,13
D16S5398,9
D18S5116,19
D19S43315
D21S1127,28
FGA19,23
TH019.3,10
TPOX8,9
vWA15,18

Run an STR similarity search on this cell line
Web pages http://www.cccells.org/dl/NB_Data_Sheets/SMS-LHN_Cell_Line_Data_Sheet_COGcell_org.pdf
Publications

PubMed=7037175
Reynolds C.P., Reynolds D.A., Frenkel E.P., Smith R.G.
Selective toxicity of 6-hydroxydopamine and ascorbate for human neuroblastoma in vitro: a model for clearing marrow prior to autologous transplant.
Cancer Res. 42:1331-1336(1982)

PubMed=8242562; DOI=10.1002/1097-0142(19931201)72:11<3346::AID-CNCR2820721134>3.0.CO;2-E
Wada R.K., Seeger R.C., Brodeur G.M., Einhorn P.A., Rayner S.A., Tomayko M.M., Reynolds C.P.
Human neuroblastoma cell lines that express N-myc without gene amplification.
Cancer 72:3346-3354(1993)

DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999)

PubMed=11507071
Keshelava N., Zuo J.J., Chen P., Waidyaratne S.N., Luna M.C., Gomer C.J., Triche T.J., Reynolds C.P.
Loss of p53 function confers high-level multidrug resistance in neuroblastoma cell lines.
Cancer Res. 61:6185-6193(2001)

PubMed=15720811; DOI=10.1593/neo.04310; PMCID=PMC1531688
Walton J.D., Kattan D.R., Thomas S.K., Spengler B.A., Guo H.-F., Biedler J.L., Cheung N.-K.V., Ross R.A.
Characteristics of stem cells from human neuroblastoma cell lines and in tumors.
Neoplasia 6:838-845(2004)

PubMed=15892104; DOI=10.1002/gcc.20198
Mosse Y.P., Greshock J., Margolin A.A., Naylor T., Cole K.A., Khazi D., Hii G., Winter C., Shahzad S., Asziz M.U., Biegel J.A., Weber B.L., Maris J.M.
High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
Genes Chromosomes Cancer 43:390-403(2005)

PubMed=24792489; DOI=10.1007/s11060-014-1456-8
Farooqi A.S., Dagg R.A., Choi L.M.R., Shay J.W., Reynolds C.P., Lau L.M.S.
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
J. Neurooncol. 119:17-26(2014)

Cross-references
Encyclopedic resources Wikidata; Q54954993
Polymorphism and mutation databases Cosmic; 717429
Cosmic; 848931
IARC_TP53; 23821
Entry history
Entry creation06-Jun-2012
Last entry update21-Mar-2023
Version number15