• Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Heterozygous; Note=Only detected in 5% of the cells in early passages but increase to 50% in late passages (PubMed=31452835).
  
• Mutation; HGNC; HGNC:427; ALK; Simple; p.Leu1196Met (c.3586C>A); ClinVar=VCV000376135; Zygosity=Heterozygous; Note=Only detected in 0.45% of the cells in early passages but increase to 32% in late passages (PubMed=31452835).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asn235Ser (c.704A>G); ClinVar=VCV000127821; Zygosity=Unspecified (PubMed=18534018).
  

DOI=10.1007/0-306-46872-7_2
Thiele C.J.
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PubMed=18534018; DOI=10.1186/1476-4598-7-50; PMCID=PMC2442611
Combaret V., Boyault S., Iacono I., Brejon S., Rousseau R., Puisieux A.
Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity.
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PubMed=20160348; DOI=10.1172/JCI41013; PMCID=PMC2827960
Bouzas-Rodriguez J., Cabrera J.R., Delloye-Bourgeois C., Ichim G., Delcros J.-G., Raquin M.-A., Rousseau R., Combaret V., Benard J., Tauszig-Delamasure S., Mehlen P.
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PubMed=31452835; DOI=10.18632/oncotarget.27119; PMCID=PMC6697636
Durand S., Pierre-Eugene C., Mirabeau O., Louis-Brennetot C., Combaret V., Colmet-Daage L., Blanchard O., Bellini A., Daudigeos-Dubus E., Raynal V., Schleiermacher G., Baulande S., Delattre O., Janoueix-Lerosey I.
ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations.
Oncotarget 10:4937-4950(2019)