Cellosaurus cell line AR230 (CVCL

Cellosaurus AR230 (CVCL_9478)

[Text version]

Cell line name

AR230

Synonyms

AR-230

Accession

CVCL_9478

Resource Identification Initiative

To cite this cell line use: AR230 (RRID:CVCL_9478)

Comments

Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.

Sequence variations

Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=Mu-BCR transcript (PubMed=7606740; PubMed=10071072; PubMed=10576511).

Disease

Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_DP56 (AR230-r)

CVCL_DP53 (AR230-rn)

CVCL_UC13 (AR230-s)

Sex of cell

Female

Age at sampling

52Y

Category

Cancer cell line

Publications

PubMed=7606740
Wada H., Mizutani S., Nishimura J., Usuki Y., Kohsaki M., Komai M., Kaneko H., Sakamoto S., Delia D., Kanamaru A., Kakishita E.
Establishment and molecular characterization of a novel leukemic cell line with Philadelphia chromosome expressing p230 BCR/ABL fusion protein.
Cancer Res. 55:3192-3196(1995)

PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9
Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.
ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.
Leuk. Res. 23:1055-1060(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references

Encyclopedic resources

Wikidata; Q54750353

Polymorphism and mutation databases

Cosmic; 787490
Cosmic; 1026575
Cosmic; 2364007

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number