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Cellosaurus K562-H (CVCL_9121)

[Text version]
Cell line name K562-H
Accession CVCL_9121
Resource Identification Initiative To cite this cell line use: K562-H (RRID:CVCL_9121)
Comments Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=7689892; DOI=10.1248/bpb.16.548
Sasaki D., Kosunago S., Hirano J., Matsuda K., Hata Y., Komiyama Y., Mikami T., Matsumoto T., Suzuki M.
Cloning and characterization of K562 cells on hemoglobin synthetic activity.
Biol. Pharm. Bull. 16:548-551(1993)

Cross-references
Encyclopedic resources Wikidata; Q54899388
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number19