Cellosaurus cell line 27b (CVCL

Cellosaurus 27b (CVCL_8997)

Cross-references
Cell line name	27b
Synonyms	iPS-27b; hiPS-27b; hiPS 27b; 27b-ALS; SOD1-27b; HVRDi008-B; HVRDi012-A
Accession	CVCL_8997
Resource Identification Initiative	To cite this cell line use: 27b (RRID:CVCL_8997)
Comments	From: Harvard University; Boston; USA. Omics: Transcriptome analysis by microarray. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; 11179; SOD1; Simple; p.Gly86Ser (c.256G>A) (G85S); ClinVar=VCV000932081; Zygosity=Unspecified (PubMed=21293464).
Disease	Amyotrophic lateral sclerosis 1 (NCIt: C168749) Amyotrophic lateral sclerosis (ORDO: Orphanet_803)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_8998 ! 27e
Sex of cell	Female
Age at sampling	29Y
Category	Induced pluripotent stem cell
Publications	PubMed=21293464; DOI=10.1038/nbt.1783; PMCID=PMC3229307 Boulting G.L., Kiskinis E., Croft G.F., Amoroso M.W., Oakley D.H., Wainger B.J., Williams D.J., Kahler D.J., Yamaki M., Davidow L.S., Rodolfa C.T., Dimos J.T., Mikkilineni S., MacDermott A.B., Woolf C.J., Henderson C.E., Wichterle H., Eggan K.C. A functionally characterized test set of human induced pluripotent stem cells. Nat. Biotechnol. 29:279-286(2011) PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454 Bock C., Kiskinis E., Verstappen G., Gu H.-C., Boulting G.L., Smith Z.D., Ziller M.J., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K.C., Meissner A. Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell 144:439-452(2011)
Cell line databases/resources	hPSCreg; HVRDi008-B
Biological sample resources	ENCODE; ENCBS466JVT
Encyclopedic resources	Wikidata; Q54583763
Experimental variables resources	EFO; EFO_0007109
Gene expression databases	GEO; GSM637788 GEO; GSM670070
Entry history
Entry creation	06-Jun-2012
Last entry update	10-Sep-2024
Version number	22