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Cellosaurus SYF + c-Src (CVCL_8976)

[Text version]
Cell line name SYF + c-Src
Accession CVCL_8976
Resource Identification Initiative To cite this cell line use: SYF + c-Src (RRID:CVCL_8976)
Comments Knockout cell: Method=KO mouse; MGI; MGI:95602; Fyn.
Knockout cell: Method=KO mouse; MGI; MGI:98397; Src.
Knockout cell: Method=KO mouse; MGI; MGI:99147; Yes1.
Genetic integration: Method=Transduction; Gene=MGI; MGI:98397; Src.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_6461 (SYF)
Sex of cell Sex unspecified
Age at sampling 9-10FD
Category Transformed cell line
Publications

PubMed=10228160; DOI=10.1093/emboj/18.9.2459; PMCID=PMC1171328
Klinghoffer R.A., Sachsenmaier C., Cooper J.A., Soriano P.
Src family kinases are required for integrin but not PDGFR signal transduction.
EMBO J. 18:2459-2471(1999)

Cross-references
Cell line collections (Providers) ATCC; CRL-2498
Cell line databases/resources CLO; CLO_0009234
Encyclopedic resources Wikidata; Q54971268
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number14