| Cell line name |
U937(CD59-) |
|---|
| Synonyms |
CD59- U937 |
|---|
| Accession |
CVCL_8932 |
|---|
| Resource Identification Initiative |
To cite this cell line use: U937(CD59-) (RRID:CVCL_8932) |
|---|
| Comments |
Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175. |
|---|
| Sequence variations |
- Gene fusion; HGNC; HGNC:16063; MLLT10 + HGNC; HGNC:15514; PICALM; Name(s)=PICALM-MLLT10, CALM-AF10 (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gly129fs*51 (c.387_388insCGCC); Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; HGNC:9644; PTPN11; Simple; p.Gly60Arg (c.178G>C); ClinVar=VCV000372590; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; c.559+1G>A (p.Val173Trpfs*59); ClinVar=VCV000428908; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
- Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg301Ter (c.901C>T) (p.Arg352Ter, c.1054C>T) (p.Arg374Ter, c.1120C>T); ClinVar=VCV000449416; Zygosity=Heterozygous (from parent cell line).
|
|---|
| Disease |
Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_0007 (U-937) |
|---|
| Sex of cell |
Male |
|---|
| Age at sampling |
37Y |
|---|
| Category |
Cancer cell line |
|---|
| Publications | PubMed=7518799; PMCID=PMC1422381
van den Berg C.W., Williams O.M., Morgan B.P.
Presence of a dysfunctional form of CD59 on a CD59+ subclone of the U937 cell line.
Immunology 81:637-642(1994) |
|---|
| Cross-references |
|---|
| Cell line databases/resources |
cancercelllines; CVCL_8932
|
|---|
| Encyclopedic resources |
Wikidata; Q54973789
|
|---|
| Entry history |
|---|
| Entry creation | 06-Jun-2012 |
|---|
| Last entry update | 19-Dec-2024 |
|---|
| Version number | 17 |
|---|
