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Cellosaurus CHO DP-12 clone#1934 (CVCL_8845)

[Text version]
Cell line name CHO DP-12 clone#1934
Synonyms CHO DP-12, clone#1934 aIL8.92 NB 28605/14
Accession CVCL_8845
Resource Identification Initiative To cite this cell line use: CHO DP-12 clone#1934 (RRID:CVCL_8845)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12445.
Characteristics: Expresses the variable light and heavy chains of the mAB 6G4.2.5 produced by the hybridoma of the same name (Cellosaurus=CVCL_J003).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_8844 (CHO DP-12)
Children:
CVCL_T062 (CHO-M1)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

Patent=US6025158
Gonzalez T.N., Leong S.R., Presta L.G.
Nucleic acids encoding humanized anti-IL-8 monoclonal antibodies.
Patent number US6025158, 15-Dec-2000

PubMed=22373341; DOI=10.1186/1753-6561-5-S8-P29; PMCID=PMC3284905
Heinrich C., Wolf T., Kropp C., Northoff S., Noll T.
Growth characterization of CHO DP-12 cell lines with different high passage histories.
BMC Proc. 5 Suppl. 8:P29-P29(2011)

Cross-references
Cell line collections (Providers) ATCC; CRL-3614
ATCC; CRL-12445 - Discontinued
Cell line databases/resources CLO; CLO_0002425
Encyclopedic resources Wikidata; Q54812581
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number12