ID   M-MOK
AC   CVCL_8731
DR   CLO; CLO_0051548
DR   BioSample; SAMN03471920
DR   Cosmic; 787456
DR   Cosmic; 975273
DR   Cosmic; 1281331
DR   RCB; RCB2534
DR   TKG; TKG 0458
DR   Wikidata; Q38518614
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=7589286;
RX   PubMed=8558913;
RX   PubMed=9096695;
CC   Population: Japanese.
CC   Characteristics: Requires human fibroblast feeder cells for its viability.
CC   Characteristics: CSF2 dependent.
CC   Doubling time: 45 +- 6 hours (PubMed=9096695).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): RCB=RCB2534; TKG=TKG 0458
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12,14
ST   D16S539: 10,12
ST   D5S818: 9,11
ST   D7S820: 10
ST   TH01: 7
ST   TPOX: 11,12
ST   vWA: 17,18
DI   NCIt; C7972; Childhood acute megakaryoblastic leukemia
DI   ORDO; Orphanet_518; Acute megakaryoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   1Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 15
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=7589286;
RA   Itano M., Tsuchiya S., Minegishi N., Fujie H., Minegishi M.,
RA   Morita S., Yambe T., Ohashi Y., Masuda T., Koike T., Konno T.;
RT   "Establishment and characterization of a novel human immature
RT   megakaryoblastic leukemia cell line, M-MOK, dependent on fibroblasts
RT   for its viability.";
RL   Exp. Hematol. 23:1301-1309(1995).
//
RX   PubMed=8558913;
RA   Morita S., Tsuchiya S., Fujie H., Itano M., Ohashi Y., Minegishi M.,
RA   Imaizumi M., Endo M., Takano N., Konno T.;
RT   "Cell surface c-kit receptors in human leukemia cell lines and
RT   pediatric leukemia: selective preservation of c-kit expression on
RT   megakaryoblastic cell lines during adaptation to in vitro culture.";
RL   Leukemia 10:102-105(1996).
//
RX   PubMed=9096695; DOI=10.1038/sj.leu.2400621;
RA   Drexler H.G., Zaborski M., Quentmeier H.;
RT   "Thrombopoietin supports the continuous growth of cytokine-dependent
RT   human leukemia cell lines.";
RL   Leukemia 11:541-551(1997).
//