ID   HOC927
AC   CVCL_8704
DR   cancercelllines; CVCL_8704
DR   Cosmic; 1123035
DR   IARC_TP53; 24377
DR   Wikidata; Q54890121
RX   PubMed=1570156;
RX   PubMed=1624295;
RX   PubMed=10069537;
RX   PubMed=18097548;
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Homozygous (PubMed=18097548).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=1570156).
CC   Derived from site: In situ; Lymph node; UBERON=UBERON_0000029.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 19
//
RX   PubMed=1570156;
RA   Sakai E., Tsuchida N.;
RT   "Most human squamous cell carcinomas in the oral cavity contain
RT   mutated p53 tumor-suppressor genes.";
RL   Oncogene 7:927-933(1992).
//
RX   PubMed=1624295; DOI=10.1002/hed.2880140103;
RA   Rikimaru K., Tadokoro K., Yamamoto T., Enomoto S., Tsuchida N.;
RT   "Gene amplification and overexpression of epidermal growth factor
RT   receptor in squamous cell carcinoma of the head and neck.";
RL   Head Neck 14:8-13(1992).
//
RX   PubMed=10069537; DOI=10.1111/j.1600-0714.1999.tb02006.x;
RA   Hoteiya T., Hayashi E., Satomura K., Kamata N., Nagayama M.;
RT   "Expression of E-cadherin in oral cancer cell lines and its
RT   relationship to invasiveness in SCID mice in vivo.";
RL   J. Oral Pathol. Med. 28:107-111(1999).
//
RX   PubMed=18097548; DOI=10.3892/ijo.32.1.101;
RA   Murugan A.K., Hong N.T., Fukui Y., Munirajan A.K., Tsuchida N.;
RT   "Oncogenic mutations of the PIK3CA gene in head and neck squamous cell
RT   carcinomas.";
RL   Int. J. Oncol. 32:101-111(2008).
//