ID   HOC719-NE
AC   CVCL_8701
SY   HOC719-Negative E-cadherin
DR   Wikidata; Q54890117
RX   PubMed=11120485;
RX   PubMed=12632084;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Met1043Val (c.3127A>G); ClinVar=VCV000376485; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp281Glu (c.843C>G); ClinVar=VCV000376587; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_8700 ! HOC719
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 15
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RX   PubMed=11120485; DOI=10.1016/S1368-8375(00)00059-2;
RA   Yokoyama K., Kamata N., Hayashi E., Hoteiya T., Ueda N., Fujimoto R.,
RA   Nagayama M.;
RT   "Reverse correlation of E-cadherin and snail expression in oral
RT   squamous cell carcinoma cells in vitro.";
RL   Oral Oncol. 37:65-71(2001).
//
RX   PubMed=12632084; DOI=10.3892/ijo.22.4.891;
RA   Yokoyama K., Kamata N., Fujimoto R., Tsutsumi S., Tomonari M.,
RA   Taki M., Hosokawa H., Nagayama M.;
RT   "Increased invasion and matrix metalloproteinase-2 expression by
RT   Snail-induced mesenchymal transition in squamous cell carcinomas.";
RL   Int. J. Oncol. 22:891-898(2003).
//