ID   Detroit 30A
AC   CVCL_8674
SY   Detroit-30A; Det-30A; Det30A
DR   BioSample; SAMN03151680
DR   Wikidata; Q54830984
RX   PubMed=1246601;
RX   PubMed=5668122;
RX   PubMed=13307201;
RX   PubMed=13370509;
RX   PubMed=13460970;
RX   PubMed=20143388;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=20143388). Originally thought to originate from the ascitic fluid of a 43 year old breast cancer patient.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00041.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 22
//
RX   PubMed=1246601; DOI=10.1126/science.1246601;
RA   Nelson-Rees W.A., Flandermeyer R.R.;
RT   "HeLa cultures defined.";
RL   Science 191:96-98(1976).
//
RX   PubMed=5668122; DOI=10.3181/00379727-128-33119;
RA   Peterson W.D. Jr., Stulberg C.S., Swanborg N.K., Robinson A.R.;
RT   "Glucose-6-phosphate dehydrogenase isoenzymes in human cell cultures
RT   determined by sucrose-agar gel and cellulose acetate zymograms.";
RL   Proc. Soc. Exp. Biol. Med. 128:772-776(1968).
//
RX   PubMed=13307201;
RA   Berman L., Stulberg C.S., Ruddle F.H.;
RT   "Epithelium-like cells derived from tissue cultures of human bone
RT   marrow and ascitic fluid.";
RL   J. Mich. State Med. Soc. 55:269-271(1956).
//
RX   PubMed=13370509; DOI=10.3181/00379727-92-22595;
RA   Berman L., Stulberg C.S.;
RT   "Eight culture strains (Detroit) of human epithelial-like cells.";
RL   Proc. Soc. Exp. Biol. Med. 92:730-735(1956).
//
RX   PubMed=13460970;
RA   Berman L., Stulberg C.S., Ruddle F.H.;
RT   "Human cell culture: morphology of the Detroit strains.";
RL   Cancer Res. 17:668-676(1957).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//