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Cellosaurus Rh41-807R (CVCL_8670)

[Text version]
Cell line name Rh41-807R
Accession CVCL_8670
Resource Identification Initiative To cite this cell line use: Rh41-807R (RRID:CVCL_8670)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_88339; BMS-754807.
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Gene fusion; HGNC; HGNC:3819; FOXO1 + HGNC; HGNC:8617; PAX3; Name(s)=PAX3-FOXO1, PAX3-FKHR (from parent cell line).
Disease Alveolar rhabdomyosarcoma (NCIt: C3749)
Alveolar rhabdomyosarcoma (ORDO: Orphanet_99756)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2176 (Rh41)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=20807811; DOI=10.1158/0008-5472.CAN-10-0391
Huang F., Hurlburt W., Greer A., Reeves K.A., Hillerman S., Chang H., Fargnoli J., Finckenstein F.G., Gottardis M.M., Carboni J.M.
Differential mechanisms of acquired resistance to insulin-like growth factor-I receptor antibody therapy or to a small-molecule inhibitor, BMS-754807, in a human rhabdomyosarcoma model.
Cancer Res. 70:7221-7231(2010)

Cross-references
Encyclopedic resources Wikidata; Q54950359
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16