Cellosaurus cell line VACO 425 (CVCL

Cellosaurus VACO 425 (CVCL_8633)

Cross-references
Cell line name	VACO 425
Synonyms	VACO425; Vaco 425; Vaco425; V425
Accession	CVCL_8633
Resource Identification Initiative	To cite this cell line use: VACO 425 (RRID:CVCL_8633)
Comments	Microsatellite instability: Stable (MSS) (PubMed=27004849). Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations	Mutation; HGNC; HGNC:30881; ALG13; Simple; p.Glu729Ter (c.2185G>T); Zygosity=Unspecified (PubMed=27004849). Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=27004849).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Category	Cancer cell line
Publications	PubMed=8385345; DOI=10.1073/pnas.90.7.2846; PMCID=PMC46193 Smith K.J., Johnson K.A., Bryan T.M., Hill D.E., Markowitz S.D., Willson J.K.V., Paraskeva C., Petersen G.M., Hamilton S.R., Vogelstein B., Kinzler K.W. The APC gene product in normal and tumor cells. Proc. Natl. Acad. Sci. U.S.A. 90:2846-2850(1993) PubMed=27004849; DOI=10.1038/srep23642; PMCID=PMC4804330 Venkitachalam S., Revoredo L., Varadan V., Fecteau R.E., Ravi L., Lutterbaugh J.D., Markowitz S.D., Willis J.E., Gerken T.A., Guda K. Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer. Sci. Rep. 6:23642-23642(2016)
Cell line databases/resources	cancercelllines; CVCL_8633
Encyclopedic resources	Wikidata; Q54992729
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	14