ID   MGR2
AC   CVCL_8564
SY   MGR 2; UWR2; UWR-2
DR   EFO; EFO_0022671
DR   cancercelllines; CVCL_8564
DR   IARC_TP53; 26930
DR   Wikidata; Q54905491
RX   DOI=10.1007/0-306-46861-1_11;
RX   PubMed=2208164;
RX   PubMed=18505928;
RX   PubMed=19706761;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (PubMed=18505928).
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   65Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 16
//
RX   DOI=10.1007/0-306-46861-1_11;
RA   Ali-Osman F.;
RT   "Brain tumors.";
RL   (In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York; USA (1999).
//
RX   PubMed=2208164;
RA   Ali-Osman F., Stein D.E., Renwick A.;
RT   "Glutathione content and glutathione-S-transferase expression in
RT   1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human malignant
RT   astrocytoma cell lines.";
RL   Cancer Res. 50:6976-6980(1990).
//
RX   PubMed=18505928; DOI=10.1158/1541-7786.MCR-07-2105; PMCID=PMC2570202;
RA   Lo H.-W., Stephenson L., Cao X.-Y., Milas M., Pollock R.E., Ali-Osman F.;
RT   "Identification and functional characterization of the human
RT   glutathione S-transferase P1 gene as a novel transcriptional target of
RT   the p53 tumor suppressor gene.";
RL   Mol. Cancer Res. 6:843-850(2008).
//
RX   PubMed=19706761; DOI=10.1158/0008-5472.CAN-09-0886; PMCID=PMC2771365;
RA   Lo H.-W., Zhu H., Cao X.-Y., Aldrich A., Ali-Osman F.;
RT   "A novel splice variant of GLI1 that promotes glioblastoma cell
RT   migration and invasion.";
RL   Cancer Res. 69:6790-6798(2009).
//