Cellosaurus cell line MGR1 (CVCL

Cellosaurus MGR1 (CVCL_8563)

Cross-references
Cell line name	MGR1
Synonyms	MGR 1; MGR-1; UWR1; UWR-1
Accession	CVCL_8563
Resource Identification Initiative	To cite this cell line use: MGR1 (RRID:CVCL_8563)
Comments	Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr155Asn (c.464C>A); ClinVar=VCV000406564; Zygosity=Unspecified (PubMed=18505928).
Disease	Anaplastic astrocytoma (NCIt: C9477) Anaplastic astrocytoma (ORDO: Orphanet_251589)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	42Y
Category	Cancer cell line
Publications	PubMed=2208164 Ali-Osman F., Stein D.E., Renwick A. Glutathione content and glutathione-S-transferase expression in 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human malignant astrocytoma cell lines. Cancer Res. 50:6976-6980(1990) DOI=10.1007/0-306-46861-1_11 Ali-Osman F. Brain tumors. (In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York; USA (1999) PubMed=18505928; DOI=10.1158/1541-7786.MCR-07-2105; PMCID=PMC2570202 Lo H.-W., Stephenson L., Cao X.-Y., Milas M., Pollock R.E., Ali-Osman F. Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene. Mol. Cancer Res. 6:843-850(2008)
Cell line databases/resources	cancercelllines; CVCL_8563
Encyclopedic resources	Wikidata; Q54905490
Experimental variables resources	EFO; EFO_0022670
Polymorphism and mutation databases	IARC_TP53; 26931
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	17