ID   Mel20-07-070
AC   CVCL_8475
SY   MEL20-07-070
DR   cancercelllines; CVCL_8475
DR   Cosmic; 1665025
DR   Wikidata; Q54905158
RX   PubMed=21386926;
RX   PubMed=22515704;
CC   Sequence variation: Mutation; HGNC; HGNC:4379; GNA11; Simple; p.Gln209Leu (c.626A>T); ClinVar=VCV000376002; Zygosity=Heterozygous (PubMed=22515704).
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C7712; Uveal melanoma
DI   ORDO; Orphanet_39044; Uveal melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 15
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RX   PubMed=21386926; PMCID=PMC3049736;
RA   Burgess B.L., Rao N.P., Eskin A., Nelson S.F., McCannel T.A.;
RT   "Characterization of three cell lines derived from fine needle biopsy
RT   of choroidal melanoma with metastatic outcome.";
RL   Mol. Vis. 17:607-615(2011).
//
RX   PubMed=22515704; DOI=10.1186/1476-4598-11-22; PMCID=PMC3444881;
RA   von Euw E.M., Atefi M., Attar N., Chu C., Zachariah S., Burgess B.L.,
RA   Mok S., Ng C., Wong D.J.L., Chmielowski B., Lichter D.I., Koya R.C.,
RA   McCannel T.A., Izmailova E., Ribas A.;
RT   "Antitumor effects of the investigational selective MEK inhibitor
RT   TAK733 against cutaneous and uveal melanoma cell lines.";
RL   Mol. Cancer 11:22.1-22.9(2012).
//