ID   C918
AC   CVCL_8471
DR   cancercelllines; CVCL_8471
DR   CLS; 305109
DR   Cosmic; 1320367
DR   Cosmic; 1669120
DR   Wikidata; Q54808274
RX   PubMed=8683940;
RX   PubMed=10952317;
RX   PubMed=18689700;
RX   PubMed=22383533;
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (PubMed=22383533).
CC   Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3111C0001CCC000216). It was one of the sources for the STR profile of this entry.
ST   Source(s): CCRID; PubMed=18689700
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 11
ST   D16S539: 8,12
ST   D18S51: 15
ST   D19S433: 13,14
ST   D21S11: 30
ST   D2S1338: 24,25
ST   D3S1358: 16
ST   D5S818: 11,12
ST   D7S820: 12
ST   D8S1179: 13
ST   FGA: 20,21
ST   TH01: 8,9.3
ST   TPOX: 11
ST   vWA: 16,17
DI   NCIt; C7712; Uveal melanoma
DI   ORDO; Orphanet_39044; Uveal melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_8472 ! M619
OI   CVCL_3447 ! MuM-2B
SX   Female
AG   60Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 19
//
RX   PubMed=8683940;
RA   Daniels K.J., Boldt H.C., Martin J.A., Gardner L.M., Meyer M.,
RA   Folberg R.;
RT   "Expression of type VI collagen in uveal melanoma: its role in pattern
RT   formation and tumor progression.";
RL   Lab. Invest. 75:55-66(1996).
//
RX   PubMed=10952317; DOI=10.1038/35020115;
RA   Bittner M., Meltzer P.S., Chen Y.-D., Jiang Y., Seftor E.A.,
RA   Hendrix M.J.C., Radmacher M.D., Simon R.M., Yakhini Z., Ben-Dor A.,
RA   Sampas N., Dougherty E.R., Wang E., Marincola F.M., Gooden G.C., Lueders J.,
RA   Glatfelter A., Pollock P.M., Carpten J.D., Gillanders E.M., Leja D.,
RA   Dietrich K., Beaudry C., Berens M.E., Alberts D.S., Sondak V.K.,
RA   Hayward N.K., Trent J.M.;
RT   "Molecular classification of cutaneous malignant melanoma by gene
RT   expression profiling.";
RL   Nature 406:536-540(2000).
//
RX   PubMed=18689700; DOI=10.1167/iovs.08-2324; PMCID=PMC2576485;
RA   Folberg R., Kadkol S.S., Frenkel S., Valyi-Nagy K., Jager M.J.,
RA   Pe'er J., Maniotis A.J.;
RT   "Authenticating cell lines in ophthalmic research laboratories.";
RL   Invest. Ophthalmol. Vis. Sci. 49:4697-4701(2008).
//
RX   PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676;
RA   Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V.,
RA   Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M.,
RA   Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.;
RT   "A high-throughput panel for identifying clinically relevant mutation
RT   profiles in melanoma.";
RL   Mol. Cancer Ther. 11:888-897(2012).
//