ID   CaVe
AC   CVCL_8444
SY   Cancer Ventriculi
DR   BioSample; SAMN03151671
DR   Wikidata; Q54808631
RX   PubMed=58478;
RX   PubMed=6451928;
RX   PubMed=11942358;
RX   PubMed=14071827;
RX   PubMed=20143388;
CC   Group: Space-flown cell line (cellonaut).
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=58478; PubMed=6451928; PubMed=20143388). Originally thought to originate from a gastric carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00036.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Anecdotal: Have been flown in space on Zond-5 to study growth in microgravity (PubMed=11942358).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 23
RX   PubMed=58478;
RA   Kulagina O.E., Muzurenko N.P., Pogosiants E.E.;
RT   "Karyotypic analysis of human cell lines (CaVe and HeLa) by the method
RT   of differential staining of chromosomes.";
RL   Vopr. Virusol. 20:677-681(1975).
RX   PubMed=6451928; DOI=10.1126/science.6451928;
RA   Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.;
RT   "Cross-contamination of cells in culture.";
RL   Science 212:446-452(1981).
RX   PubMed=11942358;
RA   Zhukov-Verezhnikov N.N., Volkov M.N., Maisky I.N., Rybakov N.I.,
RA   Guberniev M.A., Podoplelov I.I., Kulagin A.N., Aniskin E.D.,
RA   Rybakova K.D., Sharyi N.I., Voronkova I.P., Saxonov P.P., Kopyev V.Y.,
RA   Antipov V.V., Kozlov V.A., Parfyonov G.P., Orlovsky V.I.;
RT   "Experiments with micro-organisms and human cell cultures in the Zond
RT   5 and Zond 7 flights.";
RL   Life Sci. Space Res. 9:99-103(1971).
RX   PubMed=14071827; DOI=10.1093/jnci/31.5.1173;
RA   Dobrynin Y.V.;
RT   "Establishment and characteristics of cell strains from some
RT   epithelial tumors of human origin.";
RL   J. Natl. Cancer Inst. 31:1173-1195(1963).
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).