ID   PEAZ-1
AC   CVCL_8437
DR   BioSample; SAMN03151782
DR   cancercelllines; CVCL_8437
DR   Cell_Model_Passport; SIDM00830
DR   Wikidata; Q54946897
RX   CelloPub=CLPUB00698;
RX   PubMed=11433418;
RX   PubMed=20143388;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HT-1080 derivative (PubMed=20143388; CelloPub=CLPUB00698). Originally thought to originate from a prostate carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00257.
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
ST   Source(s): CelloPub=CLPUB00698
ST   Amelogenin: X,Y
ST   D13S317: 12
ST   D18S51: 12,18
ST   D21S11: 28,30
ST   D3S1358: 16
ST   D5S818: 11,13
ST   D7S820: 9,10
ST   D8S1179: 13,14
ST   FGA: 22,25
ST   vWA: 14,19
DI   NCIt; C3043; Fibrosarcoma
DI   ORDO; Orphanet_2030; Fibrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0317 ! HT-1080
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 28
//
RX   CelloPub=CLPUB00698;
RA   van Bokhoven A.;
RT   "Models for prostate cancer. Molecular characterization and critical
RT   appraisal of human prostate carcinoma cell lines.";
RL   Thesis PhD (2004), Katholieke Universiteit Nijmegen, Netherlands.
//
RX   PubMed=11433418; DOI=10.1002/pros.1084;
RA   Schmelz M., Cress A.E., Barrera J., McDaniel K.M., Davis T.L.,
RA   Fuchs L., Dalkin B.L., Nagle R.B.;
RT   "PEAZ-1: a new human prostate neoplastic epithelial cell line.";
RL   Prostate 48:79-92(2001).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//