Cellosaurus cell line Ger (CVCL

Cellosaurus Ger (CVCL_8353)

Cross-references
Cell line name	Ger
Synonyms	GER
Accession	CVCL_8353
Resource Identification Initiative	To cite this cell line use: Ger (RRID:CVCL_8353)
Comments	Doubling time: 36 hours (Note=At 11th passage) (PubMed=435363).
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=11787853). Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=11787853). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=11787853). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val272Leu (c.814G>T); ClinVar=VCV000012358; Zygosity=Unspecified (PubMed=11787853).
Disease	Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	56Y
Category	Cancer cell line
Publications	PubMed=435363; DOI=10.1038/bjc.1979.24; PMCID=PMC2009856 Grant A.G., Duke D., Hermon-Taylor J. Establishment and characterization of primary human pancreatic carcinoma in continuous cell culture and in nude mice. Br. J. Cancer 39:143-151(1979) PubMed=11787853; DOI=10.1007/s004280100474 Moore P.S., Sipos B., Orlandini S., Sorio C., Real F.X., Lemoine N.R., Gress T.M., Bassi C., Kloppel G., Kalthoff H., Ungefroren H., Lohr J.-M., Scarpa A. Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. Virchows Arch. 439:798-802(2001)
Cell line databases/resources	cancercelllines; CVCL_8353
Anatomy/cell type resources	BTO; BTO_0002865
Encyclopedic resources	Wikidata; Q54835727
Polymorphism and mutation databases	Cosmic; 710856 IARC_TP53; 16740
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	17