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Cellosaurus ED(27) (CVCL_8345)

[Text version]
Cell line name ED(27)
Synonyms ED27
Accession CVCL_8345
Resource Identification Initiative To cite this cell line use: ED(27) (RRID:CVCL_8345)
Comments Problematic cell line: Contaminated. Shown to be a WISH derivative (PubMed=11869090; PubMed=20143388). Originally thought to originate from a chorionic villus sample from a 35 year old female donor.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00191.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1909 (WISH)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=1415390; DOI=10.1016/S0002-9378(12)80036-6
Diss E.M., Gabbe S.G., Moore J.W., Kniss D.A.
Study of thromboxane and prostacyclin metabolism in an in vitro model of first-trimester human trophoblast.
Am. J. Obstet. Gynecol. 167:1046-1052(1992)

PubMed=11869090; DOI=10.1053/plac.2001.0749
Kniss D.A., Xie Y., Li Y., Kumar S., Linton E.A., Cohen P., Fan-Havard P., Redman C.W.G., Sargent I.L.
ED(27) trophoblast-like cells isolated from first-trimester chorionic villi are genetically identical to HeLa cells yet exhibit a distinct phenotype.
Placenta 23:32-43(2002)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151688
Encyclopedic resources Wikidata; Q54831952
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20