ID   MUTZ-11
AC   CVCL_8288
SY   MUTZ11; Menschliche Und Tierische Zellkulture-11
DR   Cosmic; 787415
DR   Cosmic; 975283
DR   Cosmic; 1012103
DR   Cosmic; 1281341
DR   Cosmic; 1465961
DR   Wikidata; Q54907098
RX   DOI=10.1007/978-3-642-59358-1_22;
RX   PubMed=12529668;
RX   PubMed=14671638;
RX   PubMed=15068904;
RX   PubMed=16408098;
CC   Doubling time: 64-98 hours (PubMed=15068904).
CC   Sequence variation: Mutation; HGNC; HGNC:3765; FLT3; Unexplicit; Internal tandem duplication (FLT3-ITD); ClinVar=VCV000016270; Zygosity=Unspecified (PubMed=12529668).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C7463; Acute myelomonocytic leukemia
DI   ORDO; Orphanet_517; Acute myelomonocytic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   60Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 19
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RX   DOI=10.1007/978-3-642-59358-1_22;
RA   Hu Z.-B., Quentmeier H., Meyer C., MacLeod R.A.F., Drexler H.G.;
RT   "Establishment of the two cytokine-dependent acute myeloid
RT   leukemia-derived cell lines MUTZ-8 and MUTZ-11.";
RL   (In book chapter) Acute leukemias IX. Haematology and blood transfusion, Vol. 41; Hiddemann W., Haferlach T., Unterhalt M., Buechner T., Ritter J. (eds.); pp.122-127; Springer; Berlin; Germany (2003).
//
RX   PubMed=12529668; DOI=10.1038/sj.leu.2402740;
RA   Quentmeier H., Reinhardt J., Zaborski M., Drexler H.G.;
RT   "FLT3 mutations in acute myeloid leukemia cell lines.";
RL   Leukemia 17:120-124(2003).
//
RX   PubMed=14671638; DOI=10.1038/sj.leu.2403236;
RA   Drexler H.G., Quentmeier H., MacLeod R.A.F.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   MLL gene alterations.";
RL   Leukemia 18:227-232(2004).
//
RX   PubMed=15068904; DOI=10.1016/j.leukres.2003.09.013;
RA   Hu Z.-B., Quentmeier H., Meyer C., Kaufmann M., MacLeod R.A.F.,
RA   Drexler H.G.;
RT   "New cytokine-dependent acute myeloid leukemia cell line MUTZ-11 with
RT   disomic chromosome rearrangement t(16;17).";
RL   Leuk. Res. 28:509-515(2004).
//
RX   PubMed=16408098; DOI=10.1038/sj.leu.2404081;
RA   Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.;
RT   "JAK2 V617F tyrosine kinase mutation in cell lines derived from
RT   myeloproliferative disorders.";
RL   Leukemia 20:471-476(2006).
//