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Cellosaurus AML14 [Human leukemia] (CVCL_8286)

[Text version]
Cell line name AML14 [Human leukemia]
Accession CVCL_8286
Resource Identification Initiative To cite this cell line use: AML14 [Human leukemia] (RRID:CVCL_8286)
Comments Characteristics: Can be induced to eosinophilic differentiation with CSF2, IL3 and IL5 (Kerafast=EWR001).
Doubling time: 24-36 hours (PubMed=8443379).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_0141 (AML14.3D10)CVCL_ZC59 (AML14.eos)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
Publications

PubMed=8443379; DOI=10.1182/blood.V81.5.1193.1193
Paul C.C., Tolbert M.E., Mahrer S., Singh A., Grace M.J., Baumann M.A.
Cooperative effects of interleukin-3 (IL-3), IL-5, and granulocyte-macrophage colony-stimulating factor: a new myeloid cell line inducible to eosinophils.
Blood 81:1193-1199(1993)

PubMed=8027673; DOI=10.1002/jlb.56.1.74
Paul C.C., Ackerman S.J., Mahrer S., Tolbert M.E., Dvorak A.M., Baumann M.A.
Cytokine induction of granule protein synthesis in an eosinophil-inducible human myeloid cell line, AML14.
J. Leukoc. Biol. 56:74-79(1994)

PubMed=9474744; DOI=10.1002/stem.160016
Baumann M.A., Paul C.C.
The AML14 and AML14.3D10 cell lines: a long-overdue model for the study of eosinophils and more.
Stem Cells 16:16-24(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Cell line collections (Providers) ABM; T8171
Kerafast; EWR001
Encyclopedic resources Wikidata; Q54749802
Polymorphism and mutation databases Cosmic; 975237
Cosmic; 1281304
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number13