ID   SQ-5
AC   CVCL_8273
SY   Sq-5; SQ5
DR   EFO; EFO_0002861
DR   BioSample; SAMN03151759
DR   Cosmic; 946076
DR   Cosmic; 1219091
DR   Cosmic; 1239914
DR   Cosmic; 1571743
DR   RCB; RCB0110
DR   Wikidata; Q54955605
RX   PubMed=10358721;
RX   PubMed=16105816;
RX   PubMed=16643607;
RX   PubMed=19472407;
RX   PubMed=20143388;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=16643607; PubMed=20143388). Originally thought to originate from a lung carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00269.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Discontinued: RCB; RCB0110; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 25
//
RX   PubMed=10358721; DOI=10.18926/AMO/31626;
RA   Matsushita, Akio
RA   Tabata, Masahiro
RA   Ueoka, Hiroshi
RA   Kiura, Katsuyuki
RA   Shibayama, Takuo
RA   Aoe, Keisuke
RA   Kohara, Hiroyuki
RA   Harada, Mine
RT   "Establishment of a drug sensitivity panel using human lung cancer
RT   cell lines.";
RL   Acta Med. Okayama 53:67-75(1999).
//
RX   PubMed=16105816; DOI=10.1158/0008-5472.CAN-05-0331;
RA   Nagai, Yoshiaki
RA   Miyazawa, Hitoshi
RA   No_last_name, Huqun
RA   Tanaka, Tomoaki
RA   Udagawa, Kiyoshi
RA   Kato, Motoyasu
RA   Fukuyama, Shunichiro
RA   Yokote, Akemi
RA   Kobayashi, Kunihiko
RA   Kanazawa, Minoru
RA   Hagiwara, Koichi
RT   "Genetic heterogeneity of the epidermal growth factor receptor in
RT   non-small cell lung cancer cell lines revealed by a rapid and
RT   sensitive detection system, the peptide nucleic acid-locked nucleic
RT   acid PCR clamp.";
RL   Cancer Res. 65:7276-7282(2005).
//
RX   PubMed=16643607; DOI=10.1111/j.1749-0774.2005.00007.x;
RA   Yoshino, Kaori
RA   Iimura, Emi
RA   Saijo, Kaoru
RA   Iwase, Satsuki
RA   Fukami, Kiyoko
RA   Ohno, Tadao
RA   Obata, Yuichi
RA   Nakamura, Yukio
RT   "Essential role for gene profiling analysis in the authentication of
RT   human cell lines.";
RL   Hum. Cell 19:43-48(2006).
//
RX   PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846;
RA   Blanco, Raquel
RA   Iwakawa, Reika
RA   Tang, Mo-Ying
RA   Kohno, Takashi
RA   Angulo, Barbara
RA   Pio, Ruben
RA   Montuenga, Luis M.
RA   Minna, John D.
RA   Yokota, Jun
RA   Sanchez-Cespedes, Montse
RT   "A gene-alteration profile of human lung cancer cell lines.";
RL   Hum. Mutat. 30:1199-1206(2009).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis, Amanda
RA   Theodosopoulos, George
RA   Atkin, Isobel
RA   Drexler, Hans Gunther
RA   Kohara, Arihiro
RA   MacLeod, Roderick A.F.
RA   Masters, John R.W.
RA   Nakamura, Yukio
RA   Reid, Yvonne A.
RA   Reddel, Roger Robert
RA   Freshney, Robert Ian
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//