Cellosaurus MKB-1 (CVCL_8265)
Cell line name | MKB-1 |
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Synonyms | MKB1 |
Accession | CVCL_8265 |
Resource Identification Initiative | To cite this cell line use: MKB-1 (RRID:CVCL_8265) |
Comments | Problematic cell line: Contaminated. Shown to be a CCRF-CEM derivative (PubMed=10508494; PubMed=12592342; PubMed=20143388). Originally thought to originate from a 17 year old female patient with acute myeloblastic leukemia. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00146. Population: Caucasian. Microsatellite instability: Instable (MSI) (PubMed=10739008). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: T-cell; CL=CL_0000084. |
Sequence variations |
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Disease | Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0207 (CCRF-CEM) |
Sex of cell | Female |
Age at sampling | 3Y11M |
Category | Cancer cell line |
Web pages | https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx |
Publications | PubMed=2486667 PubMed=9933131; DOI=10.1016/S0145-2126(98)00133-7 PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2 PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4 PubMed=12592342; DOI=10.1038/sj.leu.2402799 PubMed=15472075; DOI=10.1126/science.1102160 PubMed=20143388; DOI=10.1002/ijc.25242 |
Cross-references | |
Cell line databases/resources | cancercelllines; CVCL_8265 |
Biological sample resources | BioSample; SAMN03151620 |
Encyclopedic resources | Wikidata; Q54905811 |
Polymorphism and mutation databases | Cosmic; 999729
Cosmic; 1524807 Cosmic; 2649238 |
Entry history | |
Entry creation | 04-Apr-2012 |
Last entry update | 02-May-2024 |
Version number | 30 |