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Cellosaurus SCLC-86M1 (CVCL_8263)

[Text version]
Cell line name SCLC-86M1
Synonyms MAR-86MI; MAR 86MI; MAR86M1; MAR86MI; MAR 86 MI; 86MI; 86M1
Accession CVCL_8263
Resource Identification Initiative To cite this cell line use: SCLC-86M1 (RRID:CVCL_8263)
Comments Characteristics: Established from a first passage xenograft maintained in nude mice.
Doubling time: 70 hours (PubMed=2438285).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_X024 ! SCLC-86M2
Sex of cell Female
Age at sampling 74Y
Category Cancer cell line
Publications

PubMed=2438285; DOI=10.1007/BF00396382
Bepler G., Jaques G., Koehler A., Gropp C., Havemann K.
Markers and characteristics of human SCLC cell lines. Neuroendocrine markers, classical tumor markers, and chromosomal characteristics of permanent human small cell lung cancer cell lines.
J. Cancer Res. Clin. Oncol. 113:253-259(1987)

PubMed=3029138; DOI=10.1007/BF00389964
Bepler G., Jaques G., Neumann K., Aumuller G., Gropp C., Havemann K.
Establishment, growth properties, and morphological characteristics of permanent human small cell lung cancer cell lines.
J. Cancer Res. Clin. Oncol. 113:31-40(1987)

PubMed=2473086; DOI=10.1242/jcs.91.1.91
Broers J.L.V., Rot M.K., Oostendorp T., Bepler G., de Leij L.F.M.H., Carney D.N., Vooijs G.P., Ramaekers F.C.S.
Spontaneous changes in intermediate filament protein expression patterns in lung cancer cell lines.
J. Cell Sci. 91:91-108(1988)

PubMed=2574988; DOI=10.1038/bjc.1989.376; PMCID=PMC2247271
Jensen P.B., Vindelov L.L., Roed H., Demant E.J.F., Sehested M., Skovsgaard T., Hansen H.H.
In vitro evaluation of the potential of aclarubicin in the treatment of small cell carcinoma of the lung (SCCL).
Br. J. Cancer 60:838-844(1989)

PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y
Broers J.L.V., Mijnheere E.P., Rot M.K., Schaart G., Sijlmans A., Boerman O.C., Ramaekers F.C.S.
Novel antigens characteristic of neuroendocrine malignancies.
Cancer 67:619-633(1991)

PubMed=9744504; DOI=10.1038/bjc.1998.553; PMCID=PMC2063065
Damstrup L., Voldborg B.G.R., Spang-Thomsen M., Brunner N., Poulsen H.S.
In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor.
Br. J. Cancer 78:631-640(1998)

PubMed=12712436; DOI=10.1002/ijc.11106
Hansen L.T., Lundin C., Spang-Thomsen M., Petersen L.N., Helleday T.
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
Int. J. Cancer 105:472-479(2003)

Cross-references
Encyclopedic resources Wikidata; Q54952447
Polymorphism and mutation databases Cosmic; 2648019
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number14