ID   Loukes
AC   CVCL_8259
SY   LOUCKES; Louckes; Loucks
DR   cancercelllines; CVCL_8259
DR   IARC_TP53; 703
DR   NCBI_Iran; C160
DR   Wikidata; Q54902893
RX   PubMed=1915267;
RX   PubMed=3026973;
RX   PubMed=6112750;
RX   PubMed=6231253;
RX   PubMed=8896424;
RX   PubMed=9192833;
RX   PubMed=9973220;
RX   PubMed=17254797;
RX   PubMed=24590883;
CC   Virology: EBV-negative.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys238Tyr (c.713G>A); ClinVar=VCV000182935; Zygosity=Unspecified (PubMed=1915267).
CC   Misspelling: Luckes; NCBI_Iran=C160; PubMed=17254797.
CC   Misspelling: Lukes; PubMed=3026973; PubMed=6231253.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): PubMed=17254797
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 11,13
ST   D16S539: 12,13
ST   D18S51: 15
ST   D21S11: 29,30
ST   D3S1358: 15,17
ST   D5S818: 12
ST   D7S820: 10
ST   D8S1179: 12
ST   FGA: 19,20
ST   TH01: 8,10,11
ST   TPOX: 9
ST   vWA: 16,19
DI   NCIt; C2912; Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 26
//
RX   PubMed=1915267; DOI=10.1002/j.1460-2075.1991.tb07837.x; PMCID=PMC452998;
RA   Farrell P.J., Allan G.J., Shanahan F., Vousden K.H., Crook T.;
RT   "p53 is frequently mutated in Burkitt's lymphoma cell lines.";
RL   EMBO J. 10:2879-2887(1991).
//
RX   PubMed=3026973; DOI=10.1002/ijc.2910390215;
RA   Ehlin-Henriksson B., Manneborg-Sandlund A., Klein G.;
RT   "Expression of B-cell-specific markers in different Burkitt lymphoma
RT   subgroups.";
RL   Int. J. Cancer 39:211-218(1987).
//
RX   PubMed=6112750; DOI=10.1073/pnas.78.3.1930; PMCID=PMC319249;
RA   van Santen V.L., Cheung A., Kieff E.D.;
RT   "Epstein-Barr virus RNA VII: size and direction of transcription of
RT   virus-specified cytoplasmic RNAs in a transformed cell line.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:1930-1934(1981).
//
RX   PubMed=6231253; DOI=10.1002/ijc.2910330407;
RA   Ehlin-Henriksson B., Klein G.;
RT   "Distinction between Burkitt lymphoma subgroups by monoclonal
RT   antibodies: relationships between antigen expression and type of
RT   chromosomal translocation.";
RL   Int. J. Cancer 33:459-463(1984).
//
RX   PubMed=8896424; DOI=10.1182/blood.V88.9.3562.bloodjournal8893562;
RA   Chapman C.J., Zhou J.X., Gregory C.D., Rickinson A.B., Stevenson F.K.;
RT   "VH and VL gene analysis in sporadic Burkitt's lymphoma shows somatic
RT   hypermutation, intraclonal heterogeneity, and a role for antigen
RT   selection.";
RL   Blood 88:3562-3568(1996).
//
RX   PubMed=9192833;
RA   Cherney B.W., Bhatia K.G., Sgadari C., Gutierrez M.I., Mostowski H.S.,
RA   Pike S.E., Gupta G., Magrath I.T., Tosato G.;
RT   "Role of the p53 tumor suppressor gene in the tumorigenicity of
RT   Burkitt's lymphoma cells.";
RL   Cancer Res. 57:2508-2515(1997).
//
RX   PubMed=9973220;
RA   Gutierrez M.I., Cherney B.W., Hussain A., Mostowski H.S., Tosato G.,
RA   Magrath I.T., Bhatia K.G.;
RT   "Bax is frequently compromised in Burkitt's lymphomas with
RT   irreversible resistance to Fas-induced apoptosis.";
RL   Cancer Res. 59:696-703(1999).
//
RX   PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001;
RA   Azari S., Ahmadi N., Jeddi-Tehrani M., Shokri F.;
RT   "Profiling and authentication of human cell lines using short tandem
RT   repeat (STR) loci: report from the National Cell Bank of Iran.";
RL   Biologicals 35:195-202(2007).
//
RX   PubMed=24590883; DOI=10.1002/gcc.22161;
RA   Murga Penas E.-M., Schilling G., Behrmann P., Klokow M.,
RA   Vettorazzi E., Bokemeyer C., Dierlamm J.;
RT   "Comprehensive cytogenetic and molecular cytogenetic analysis of 44
RT   Burkitt lymphoma cell lines: secondary chromosomal changes
RT   characterization, karyotypic evolution, and comparison with primary
RT   samples.";
RL   Genes Chromosomes Cancer 53:497-515(2014).
//