ID   IMC-4
AC   CVCL_8247
DR   BioSample; SAMN03151722
DR   RCB; RCB0728
DR   Wikidata; Q54897518
RX   PubMed=1610070;
RX   PubMed=20143388;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=20143388). Originally thought to originate from a male patient (from which IMC-2 and IMC-3 were also supposed to be derived) with maxillary carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00319.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Discontinued: RCB; RCB0728; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 21
//
RX   PubMed=1610070; DOI=10.1177/000348949210100613;
RA   Komiyama S., Matsui K., Miyazaki H., Kudoh S., Mizoguchi H.,
RA   Shimizu N.;
RT   "Heterogeneity in epidermal growth factor responsiveness and tumor
RT   growth of human maxillary cancer cell lines.";
RL   Ann. Otol. Rhinol. Laryngol. 101:519-524(1992).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//