ID   GLC-8
AC   CVCL_8218
SY   GLC 8; GLC8
DR   cancercelllines; CVCL_8218
DR   Cosmic; 2239123
DR   GEO; GSM554390
DR   GEO; GSM986183
DR   IARC_TP53; 11283
DR   Progenetix; CVCL_8218
DR   Wikidata; Q54835924
RX   PubMed=1320893;
RX   PubMed=2838297;
RX   PubMed=2409557;
RX   PubMed=9559344;
RX   PubMed=10408787;
RX   PubMed=10709110;
RX   PubMed=20631050;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Gly (c.838A>G); ClinVar=VCV000376658; Zygosity=Unspecified (PubMed=10408787).
CC   Omics: Array-based CGH.
CC   Omics: SNP array analysis.
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
//
RX   PubMed=1320893; DOI=10.1159/000163712;
RA   Verbeeck M.A.E., Elands J.P.M., de Leij L.F.M.H., Buys C.H.C.M.,
RA   Carney D.N., Bepler G., Roebroek A.J.M., van de Ven W.J.M.,
RA   Burbach J.P.H.;
RT   "Expression of the vasopressin and gastrin-releasing peptide genes in
RT   small cell lung carcinoma cell lines.";
RL   Pathobiology 60:136-142(1992).
//
RX   PubMed=2838297; DOI=10.1016/0277-5379(88)90311-2;
RA   Postmus P.E., de Leij L.F.M.H., van der Veen A.Y., Mesander G.,
RA   Buys C.H.C.M., Elema J.D.;
RT   "Two small cell lung cancer cell lines established from rigid
RT   bronchoscope biopsies.";
RL   Eur. J. Cancer Clin. Oncol. 24:753-763(1988).
//
RX   PubMed=2409557; DOI=10.1073/pnas.82.13.4409; PMCID=PMC391110;
RA   Broers J.L.V., Carney D.N., de Leij L.F.M.H., Vooijs G.P.,
RA   Ramaekers F.C.S.;
RT   "Differential expression of intermediate filament proteins
RT   distinguishes classic from variant small-cell lung cancer cell
RT   lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:4409-4413(1985).
//
RX   PubMed=9559344; DOI=10.1002/(SICI)1098-2264(199804)21:4<326::AID-GCC6>3.0.CO;2-0;
RA   Mulligan L.M., Timmer T., Ivanchuk S.M., Campling B.G., Young L.C.,
RA   Rabbitts P.H., Sundaresan V., Hofstra R.M.W., Eng C.;
RT   "Investigation of the genes for RET and its ligand complex, GDNF/GFR
RT   alpha-I, in small cell lung carcinoma.";
RL   Genes Chromosomes Cancer 21:326-332(1998).
//
RX   PubMed=10408787; DOI=10.1097/00019606-199903000-00002;
RA   Hayes V.M., Bleeker W., Verlind E., Timmer T., Karrenbeld A.,
RA   Plukker J.T., Marx M.P., Hofstra R.M.W., Buys C.H.C.M.;
RT   "Comprehensive TP53-denaturing gradient gel electrophoresis mutation
RT   detection assay also applicable to archival paraffin-embedded
RT   tissue.";
RL   Diagn. Mol. Pathol. 8:2-10(1999).
//
RX   PubMed=10709110; DOI=10.1002/(SICI)1097-0215(20000315)85:6<871::AID-IJC22>3.0.CO;2-O;
RA   McLaughlin P.M.J., Helfrich W., Kok K., Mulder M., Hu S.W.,
RA   Brinker M.G.L., Ruiters M.H.J., de Leij L.F.M.H., Buys C.H.C.M.;
RT   "The ubiquitin-activating enzyme E1-like protein in lung cancer cell
RT   lines.";
RL   Int. J. Cancer 85:871-876(2000).
//
RX   PubMed=20631050; DOI=10.1101/gr.106252.110; PMCID=PMC2928498;
RA   Storlazzi C.T., Lonoce A., Guastadisegni M.C., Trombetta D.,
RA   D'Addabbo P., Daniele G., L'Abbate A., Macchia G., Surace C., Kok K.,
RA   Ullmann R., Purgato S., Palumbo O., Carella M., Ambros P.F.,
RA   Rocchi M.;
RT   "Gene amplification as double minutes or homogeneously staining
RT   regions in solid tumors: origin and structure.";
RL   Genome Res. 20:1198-1206(2010).
//