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Cellosaurus GLC-3 (CVCL_8212)

[Text version]
Cell line name GLC-3
Synonyms GLC 3; GLC3; OC-Tol; OC-TOL
Accession CVCL_8212
Resource Identification Initiative To cite this cell line use: GLC-3 (RRID:CVCL_8212)
Comments Doubling time: 56 hours (PubMed=2998591).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
Publications

PubMed=2998591
de Leij L.F.M.H., Postmus P.E., Buys C.H.C.M., Elema J.D., Ramaekers F.C.S., Poppema S., Brouwer M., van der Veen A.Y., Mesander G., The T.H.
Characterization of three new variant type cell lines derived from small cell carcinoma of the lung.
Cancer Res. 45:6024-6033(1985)

PubMed=2473086; DOI=10.1242/jcs.91.1.91
Broers J.L.V., Rot M.K., Oostendorp T., Bepler G., de Leij L.F.M.H., Carney D.N., Vooijs G.P., Ramaekers F.C.S.
Spontaneous changes in intermediate filament protein expression patterns in lung cancer cell lines.
J. Cell Sci. 91:91-108(1988)

PubMed=2574988; DOI=10.1038/bjc.1989.376; PMCID=PMC2247271
Jensen P.B., Vindelov L.L., Roed H., Demant E.J.F., Sehested M., Skovsgaard T., Hansen H.H.
In vitro evaluation of the potential of aclarubicin in the treatment of small cell carcinoma of the lung (SCCL).
Br. J. Cancer 60:838-844(1989)

PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y
Broers J.L.V., Mijnheere E.P., Rot M.K., Schaart G., Sijlmans A., Boerman O.C., Ramaekers F.C.S.
Novel antigens characteristic of neuroendocrine malignancies.
Cancer 67:619-633(1991)

PubMed=1314232; DOI=10.1002/ijc.2910510115
Smit E.F., de Vries E.G.E., Timmer-Bosscha H., de Leij L.F.M.H., Oosterhuis J.W., Scheper R.J., Weening J.J., Postmus P.E., Mulder N.H.
In vitro response of human small-cell lung-cancer cell lines to chemotherapeutic drugs; no correlation with clinical data.
Int. J. Cancer 51:72-78(1992)

PubMed=1320893; DOI=10.1159/000163712
Verbeeck M.A.E., Elands J.P.M., de Leij L.F.M.H., Buys C.H.C.M., Carney D.N., Bepler G., Roebroek A.J.M., van de Ven W.J.M., Burbach J.P.H.
Expression of the vasopressin and gastrin-releasing peptide genes in small cell lung carcinoma cell lines.
Pathobiology 60:136-142(1992)

PubMed=9212023; DOI=10.1016/S0360-3016(97)00245-9
Krarup M., Poulsen H.S., Spang-Thomsen M.
Cellular radiosensitivity of small-cell lung cancer cell lines.
Int. J. Radiat. Oncol. Biol. Phys. 38:191-196(1997)

PubMed=9559344; DOI=10.1002/(SICI)1098-2264(199804)21:4<326::AID-GCC6>3.0.CO;2-0
Mulligan L.M., Timmer T., Ivanchuk S.M., Campling B.G., Young L.C., Rabbitts P.H., Sundaresan V., Hofstra R.M.W., Eng C.
Investigation of the genes for RET and its ligand complex, GDNF/GFR alpha-I, in small cell lung carcinoma.
Genes Chromosomes Cancer 21:326-332(1998)

PubMed=9744504; DOI=10.1038/bjc.1998.553; PMCID=PMC2063065
Damstrup L., Voldborg B.G.R., Spang-Thomsen M., Brunner N., Poulsen H.S.
In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor.
Br. J. Cancer 78:631-640(1998)

PubMed=10408787; DOI=10.1097/00019606-199903000-00002
Hayes V.M., Bleeker W., Verlind E., Timmer T., Karrenbeld A., Plukker J.T., Marx M.P., Hofstra R.M.W., Buys C.H.C.M.
Comprehensive TP53-denaturing gradient gel electrophoresis mutation detection assay also applicable to archival paraffin-embedded tissue.
Diagn. Mol. Pathol. 8:2-10(1999)

PubMed=12712436; DOI=10.1002/ijc.11106
Hansen L.T., Lundin C., Spang-Thomsen M., Petersen L.N., Helleday T.
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
Int. J. Cancer 105:472-479(2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8212
Encyclopedic resources Wikidata; Q54835907
Polymorphism and mutation databases Cosmic; 2239120
Cosmic; 2648014
IARC_TP53; 11272
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18