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Cellosaurus GLC-14 (CVCL_8204)

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Cell line name GLC-14
Synonyms GLC 14; GLC14
Accession CVCL_8204
Resource Identification Initiative To cite this cell line use: GLC-14 (RRID:CVCL_8204)
Comments Doubling time: 65 hours (PubMed=2846164).
Omics: Array-based CGH.
Omics: SNP array analysis.
Derived from site: Metastatic; Supraclavicular lymph node; UBERON=UBERON_0035279.
Sequence variations
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_8205 ! GLC-16
CVCL_8206 ! GLC-19
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
Publications

PubMed=2846164
Berendsen H.H., de Leij L.F.M.H., de Vries E.G.E., Mesander G., Mulder N.H., de Jong B., Buys C.H.C.M., Postmus P.E., Poppema S., Sluiter H.J., The T.H.
Characterization of three small cell lung cancer cell lines established from one patient during longitudinal follow-up.
Cancer Res. 48:6891-6899(1988)

PubMed=1314232; DOI=10.1002/ijc.2910510115
Smit E.F., de Vries E.G.E., Timmer-Bosscha H., de Leij L.F.M.H., Oosterhuis J.W., Scheper R.J., Weening J.J., Postmus P.E., Mulder N.H.
In vitro response of human small-cell lung-cancer cell lines to chemotherapeutic drugs; no correlation with clinical data.
Int. J. Cancer 51:72-78(1992)

PubMed=9212023; DOI=10.1016/S0360-3016(97)00245-9
Krarup M., Poulsen H.S., Spang-Thomsen M.
Cellular radiosensitivity of small-cell lung cancer cell lines.
Int. J. Radiat. Oncol. Biol. Phys. 38:191-196(1997)

PubMed=9559344; DOI=10.1002/(SICI)1098-2264(199804)21:4<326::AID-GCC6>3.0.CO;2-0
Mulligan L.M., Timmer T., Ivanchuk S.M., Campling B.G., Young L.C., Rabbitts P.H., Sundaresan V., Hofstra R.M.W., Eng C.
Investigation of the genes for RET and its ligand complex, GDNF/GFR alpha-I, in small cell lung carcinoma.
Genes Chromosomes Cancer 21:326-332(1998)

PubMed=9744504; DOI=10.1038/bjc.1998.553; PMCID=PMC2063065
Damstrup L., Voldborg B.G.R., Spang-Thomsen M., Brunner N., Poulsen H.S.
In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor.
Br. J. Cancer 78:631-640(1998)

PubMed=10408787; DOI=10.1097/00019606-199903000-00002
Hayes V.M., Bleeker W., Verlind E., Timmer T., Karrenbeld A., Plukker J.T., Marx M.P., Hofstra R.M.W., Buys C.H.C.M.
Comprehensive TP53-denaturing gradient gel electrophoresis mutation detection assay also applicable to archival paraffin-embedded tissue.
Diagn. Mol. Pathol. 8:2-10(1999)

PubMed=10709110; DOI=10.1002/(SICI)1097-0215(20000315)85:6<871::AID-IJC22>3.0.CO;2-O
McLaughlin P.M.J., Helfrich W., Kok K., Mulder M., Hu S.W., Brinker M.G.L., Ruiters M.H.J., de Leij L.F.M.H., Buys C.H.C.M.
The ubiquitin-activating enzyme E1-like protein in lung cancer cell lines.
Int. J. Cancer 85:871-876(2000)

PubMed=12712436; DOI=10.1002/ijc.11106
Hansen L.T., Lundin C., Spang-Thomsen M., Petersen L.N., Helleday T.
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
Int. J. Cancer 105:472-479(2003)

PubMed=20631050; DOI=10.1101/gr.106252.110; PMCID=PMC2928498
Storlazzi C.T., Lonoce A., Guastadisegni M.C., Trombetta D., D'Addabbo P., Daniele G., L'Abbate A., Macchia G., Surace C., Kok K., Ullmann R., Purgato S., Palumbo O., Carella M., Ambros P.F., Rocchi M.
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure.
Genome Res. 20:1198-1206(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8204
Encyclopedic resources Wikidata; Q54835898
Gene expression databases GEO; GSM554391
Polymorphism and mutation databases Cosmic; 2239124
Cosmic; 2648013
IARC_TP53; 11282
Progenetix; CVCL_8204
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21